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Friday, September 04, 2020

Covid Update: Vitamin D, Herd Immunity

I mentioned Vitamin D a while ago, with the chart showing people w/high levels all had minor disease (a pretty stark correlation if consistent). Well, here's a recent RCT with essentially the same result again, strong enough to be very statistically significant despite the small size of the study:

Effect of Calcifediol Treatment and best Available Therapy versus best Available Therapy on Intensive Care Unit Admission and Mortality Among Patients Hospitalized for COVID-19: A Pilot Randomized Clinical study

"Of 50 patients treated with calcifediol, one required admission to the ICU (2%), while of 26 untreated patients, 13 required admission (50%)"

It's probably not going to lower your chances of getting it, but it might make the difference between a severe vs mild case if you do. Also note this is in the context of hydroxychloroquine as standard of care for both groups.

This could easily explain why African Americans have over twice the death rate, and also why there were no deaths in the large outbreak in the homeless population (homeless = outside = vitamin D).

And, as I've been saying since April (re. herd immunity thresholds):

Are We Already Reaching Herd Immunity?


[2020-10-31 Update: See also Vitamin D and survival in COVID-19 patients: A quasi-experimental study]

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Simon Funk / simonfunk@gmail.com